Ammonia → HCID 117966096, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:23][C:24](=[O:29])[CH2:25][C:26](=O)[CH3:27])[CH:5]=[CH:6][C:7]=1[NH:8][C:9]([CH3:22])([CH3:21])[CH2:10][C:11]1[CH:20]=[CH:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=1.[NH3:30]>CO>[NH2:30]/[C:26](/[CH3:27])=[CH:25]\[C:24]([NH:23][C:4]1[CH:5]=[CH:6][C:7]([NH:8][C:9]([CH3:21])([CH3:22])[CH2:10][C:11]2[CH:20]=[CH:19][C:18]3[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH:12]=2)=[C:2]([Cl:1])[CH:3]=1)=[O:29]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of N-(3-chloro-4-((2-methyl-1-(naphthalen-2-yl)propan-2-yl)amino) phenyl)-3-oxobutanamide (2.0 g, 4.89 mmol), MeOH (15 mL) and ammonia (15 mL) was stirred at rt overnight. The mixture was then concentrated in vacuo to give the title compound, which was used for next step without further purification.