2-Bromo-4-methylbenzaldehyde → (2'-Formyl-6-methoxy-5'-methyl-biphenyl-3-yl)-acetic acid ethyl ester

HRID 563738

Reaction equation

HRID 563738 reaction equation
[CH2:1]([O:3][C:4](=[O:23])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8](B2OC(C)(C)C(C)(C)O2)[CH:7]=1)[CH3:2].Br[C:25]1[CH:32]=[C:31]([CH3:33])[CH:30]=[CH:29][C:26]=1[CH:27]=[O:28]>>[CH2:1]([O:3][C:4](=[O:23])[CH2:5][C:6]1[CH:7]=[C:8]([C:25]2[CH:32]=[C:31]([CH3:33])[CH:30]=[CH:29][C:26]=2[CH:27]=[O:28])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 46452922-Bromo-4-methylbenzaldehydeHCID 58120060[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester

Product 1

HCID 58148809(2'-Formyl-6-methoxy-5'-methyl-biphenyl-3-yl)-acetic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester and 2-bromo-4-methylbenzaldehyde.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-20a23d6e838d483b87e3698e9dd9af1f
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Linked notes

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