o-Toluenesulfonyl chloride → Trans-10a-(4-chloro-benzenesulfonyl)-1,4-difluoro-6a,9,10,10a-tetrahydro-6H,7H-benzo[c]chromen-8-one
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C@@:11]23[CH2:24][CH2:23][C:18]4(OCC[O:19]4)[CH2:17][C@H:16]2[CH2:15][O:14][C:13]2[C:25]([F:30])=[CH:26][CH:27]=[C:28]([F:29])[C:12]3=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.C1(C)C(S(Cl)(=O)=O)=CC=CC=1>CC(C)=O.O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([C@@:11]23[CH2:24][CH2:23][C:18](=[O:19])[CH2:17][C@H:16]2[CH2:15][O:14][C:13]2[C:12]3=[C:28]([F:29])[CH:27]=[CH:26][C:25]=2[F:30])(=[O:10])=[O:9])=[CH:6][CH:7]=1Participants
5
