Potassium Nitrate → 5,6-Dimethyl-7-nitro-1,4-dihydro-quinoxaline-2,3-dione
Reaction equation
[CH3:1][C:2]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[C:3]=1[NH:4][C:5](=[O:14])[C:6](=[O:13])[NH:7]2.[N+:15]([O-])([O-:17])=[O:16].[K+]>OS(O)(=O)=O>[CH3:1][C:2]1[C:11]([CH3:12])=[C:10]([N+:15]([O-:17])=[O:16])[CH:9]=[C:8]2[C:3]=1[NH:4][C:5](=[O:14])[C:6](=[O:13])[NH:7]2Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution of 5,6-dimethyl-1,4dihydro-quinoxaline-2,3-dione (28.5 g, 150 mmol) in concentrated H2SO4 (50 mL) was added KNO3 (15.15 g, 150 mmol) portionwise keeping temperature below 5° C. Reaction mixture was stirred for 2 hours and poured over ice. Yellow precipitate was filtered, washed, and air dried.
Workup
- customtemperature below 5° C
- customReaction mixture
- additionpoured over ice
- filtrationYellow precipitate was filtered
- washwashed
- customair dried
Sources & evidence
- ORD record
- ord-23d5b5c36be74c2c9d69697e6bb1e80a
- Source dataset
- uspto-grants-2001_01
- Patent number
- US06172065B2
Reaction notes
Loading…