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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 568142Generated: October 27, 2026

Pyrrolidine → 1,3-Di-cyclopropylmethyl-8-pyrrolidinyl Xanthine

https://huagongshe.com/reaction/568142

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant1,3-Di-cyclopropylmethyl-8-chloroxanthineHCID 9814657—
Product1,3-Di-cyclopropylmethyl-8-pyrrolidinyl XanthineHCID 9923531—

Reaction Steps

The title compound was prepared from 1,3-di-cyclopropylmethyl-8-chloro xanthine (0.3 g, 0.0011 mol) and pyrrolidine (0.2 g, 0.0028 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt. >250° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06180791B2
Source datasetuspto-grants-2001_01
ORD IDord-40e37f5c2e1e482d8b6ae64150afcae3
Source noteuspto-grants-2001_01