N,N'-bis(3-acetylphenyl)pentanediamide → HCID 178466599, compound

HRID 568150

Reaction equation

HRID 568150 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([NH:10][C:11](=O)[CH2:12][CH2:13][CH2:14][C:15]([NH:17][C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([C:24](=[O:26])[CH3:25])[CH:19]=2)=O)[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2].[C:28]([NH:31][NH2:32])([NH2:30])=[NH:29].[ClH:33]>CO.Cl.Cl.NNC(N)=N>[ClH:33].[ClH:33].[C:28]([NH:31][N:32]=[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([C:24](=[O:26])[CH3:25])[CH:19]=1)[CH2:14][CH2:13][CH2:12][C:11](=[N:32][NH:31][C:28](=[NH:29])[NH2:30])[NH:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([C:1](=[O:3])[CH3:2])[CH:5]=1)(=[NH:30])[NH2:29]

Participants

5

Reactant 2

HCID 1010291N,N'-bis(3-acetylphenyl)pentanediamideHCID 178418668HCID 178418668, compound

Product 1

HCID 178466599HCID 178466599, compoundYield 98.2%

Reagents, catalysts & solvents 2

HCID 178478830HCID 178478830, compoundCatalystHCID 887MethanolSolvent

Procedure

N,N′-bis(3-acetylphenyl)pentanediamide (3.66 g), aminoguanidine hydrochloride (2.75 g), and aminoguanidine dihydrochloride (0.05 g) were heated in methanol (35 mL) for 18 hr. Cooling and filtration gave 5.412 g of N,N′-bis(3acetylphenyl)pentanediamide bis(amidinohydrazone) dihydrochloride, mp 187-191° C.

Workup

  1. temperatureCooling
  2. filtrationfiltration

Sources & evidence

ORD record
ord-2f5ac8b539ba4a04ab8e9caa86f405a3
Source dataset
uspto-grants-2001_01
Patent number
US06180676B2

Linked notes

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