Glycine → HCID 10176752, compound
Reaction equation
[NH2:1][CH2:2][C:3]([OH:5])=[O:4].[C:6](Cl)(=[O:15])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[OH-].[Na+]>O.CCOCC>[C:6]([NH:1][CH2:2][C:3]([OH:5])=[O:4])(=[O:15])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]Participants
6
Reactant 3
Product 1
Reagents, catalysts & solvents 2
Procedure
Glycine (20 mmol) was reacted with nonanoyl chloride (22 ml) in the presence of NaOH (40 mmol) in a mixture of water and ether as described in Example 1 Part A. The crude crystalline product (4.25 g) was recrystallized from ethyl acetate (40-50 ml) to give the title compound (3.42 g, 79.5%), m.p. 106°-109° C.
Workup
- customThe crude crystalline product (4.25 g) was recrystallized from ethyl acetate (40-50 ml)
Sources & evidence
- ORD record
- ord-53df7cdd58d64abcbaffbf5a5604cb7b
- Source dataset
- uspto-grants-1988_03
- Patent number
- US04734424
Reaction notes
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