Reaction equation
[C:1]([CH2:3][NH:4][C:5]([NH2:7])=[O:6])#[N:2].[OH-:8].[Na+].[CH3:10]O>>[CH3:10][O:8][C:1](=[NH:2])[CH2:3][NH:4][C:5]([NH2:7])=[O:6]Participants
4
Conditions
- Temperature
- 30 °C
Procedure
100 g of cyanomethylurea is combined with a mixture of 300 ml of methanol and 5 ml of 8N sodium hydroxide solution and stirred for 3 hours at 25°30° C. The mixture is allowed to cool to 20° C., the resultant product is removed by filtration, washed with a small amount of ice-cold methanol, and dried under vacuum, thus obtaining 92.6 g of (2-methoxy-2-iminoethyl)urea (=70% of theory).
Workup
- temperatureto cool to 20° C.
- customthe resultant product is removed by filtration
- washwashed with a small amount of ice-cold methanol
- customdried under vacuum
Sources & evidence
- ORD record
- ord-43abd032380c466b85186412985afc56
- Source dataset
- uspto-grants-1988_03
- Patent number
- US04734506
Linked notes
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