HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazole-6-sulfonic acid 4-aminobenzylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 4-Aminobenzylamine | HCID 427814 | — |
| Reactant | HCID 178434647 | HCID 178434647 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazole-6-sulfonic acid 4-aminobenzylamide | HCID 178434653 | 12.1% |
Reaction Steps
the title compound (15 mg) was prepared from crude 2-(5-amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonyl chloride (100 mg, 0.30 mmol), 4-aminomethylphenylamine (69 μL, 0.60 mmol) and PS-NMM (0.320 g, 0.60 mmol) in 5 mL of methanol. MS (m/z, ES+): 415.4 (M+1, 100%). Yield=12%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434720B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-4b0ecdb954e74e58a791dfea2be305b4 |
| Source note | uspto-grants-2016_09 |