3-(5-methyl-1H-imidazol-1-yl)propan-1-amine → HCID 25100201, compound
Reaction equation
[N:1]([C:4]1[S:5][C:6]([CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:7][C:8]=1[C:9]([O:11]C)=O)=[C:2]=[S:3].[CH3:20][C:21]1[N:25]([CH2:26][CH2:27][CH2:28][NH2:29])[CH:24]=[N:23][CH:22]=1>>[CH2:13]([C:6]1[S:5][C:4]2[NH:1][C:2](=[S:3])[N:29]([CH2:28][CH2:27][CH2:26][N:25]3[C:21]([CH3:20])=[CH:22][N:23]=[CH:24]3)[C:9](=[O:11])[C:8]=2[CH:7]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1Participants
3
Procedure
The compound was synthesized starting from methyl 2-isothiocyanato-5-benzylthiophene-3-carboxylate (0.10 g, 0.35 mmol) and 3-(5-methyl-1H-imidazol-1-yl)propan-1-amine (5) (0.048 g, 0.35 mmol) as described above.
Workup
- customThe compound was synthesized
Sources & evidence
- ORD record
- ord-aa2292da7ef048b2890a97a7c3c99ab0
- Source dataset
- uspto-grants-2015_05
- DOI