3-(4-Methyl-1H-imidazol-1-yl)propan-1-amine → 6-ethyl-3-[3-(4-methyl-1H-imidazol-1-yl)propyl]-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-one
Reaction equation
[CH2:1]([C:3]1[S:7][C:6]([N:8]=[C:9]=[S:10])=[C:5]([C:11]([O:13]C)=O)[CH:4]=1)[CH3:2].[CH3:15][C:16]1[N:17]=[CH:18][N:19]([CH2:21][CH2:22][CH2:23][NH2:24])[CH:20]=1>>[CH2:1]([C:3]1[S:7][C:6]2[NH:8][C:9](=[S:10])[N:24]([CH2:23][CH2:22][CH2:21][N:19]3[CH:20]=[C:16]([CH3:15])[N:17]=[CH:18]3)[C:11](=[O:13])[C:5]=2[CH:4]=1)[CH3:2]Participants
3
Procedure
The compound was synthesized starting from methyl 5-ethyl-2-isothiocyanatothiophene-3-carboxylate (0.100 g. 0.44 mmol) and 3-(4-methyl-1H-imidazol-1-yl)propan-1-amine (9) (0.061 g, 0.44 mmol) as described above.
Workup
- customThe compound was synthesized