Ranisen → HCID 178484398, compound
Reaction equation
[CH3:1][NH:2][C:3]([NH:8][CH2:9][CH2:10][S:11][CH2:12][C:13]1[O:17][C:16]([CH2:18][N:19]([CH3:21])[CH3:20])=[CH:15][CH:14]=1)=[CH:4][N+:5]([O-:7])=[O:6].[C:22]([OH:34])(=[O:33])/[CH:23]=[CH:24]/[C:25]1[CH:32]=[CH:31][C:29]([OH:30])=[C:27]([OH:28])[CH:26]=1>ClCCl>[CH3:1][NH:2][C:3]([NH:8][CH2:9][CH2:10][S:11][CH2:12][C:13]1[O:17][C:16]([CH2:18][N:19]([CH3:20])[CH3:21])=[CH:15][CH:14]=1)=[CH:4][N+:5]([O-:7])=[O:6].[C:22]([O-:34])(=[O:33])/[CH:23]=[CH:24]/[C:25]1[CH:32]=[CH:31][C:29]([OH:30])=[C:27]([OH:28])[CH:26]=1Participants
4
Reagents, catalysts & solvents 1
Procedure
A mixture of 1.57 g (0.5 cmole) of ranitidine and 0.95 g (0.5 cmole) of caffeic acid were suspended in dichloromethane (15 ml). The mixture was stirred for 2 hours 30 minutes at room temperature, was filtered, washed with dichloromethane. Dry weight 2.4 g. Quantitative yield.
Workup
- filtration