Sulfuric Acid → 1-(4-amino-3-nitrophenyl)ethanone
Reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10]C(=O)C)=[C:6]([N+:14]([O-:16])=[O:15])[CH:5]=1)(=[O:3])[CH3:2].S(=O)(=O)(O)O>O>[C:1]([C:4]1[CH:9]=[CH:8][C:7]([NH2:10])=[C:6]([N+:14]([O-:16])=[O:15])[CH:5]=1)(=[O:3])[CH3:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
N-(4-acetyl-2-nitrophenyl)acetamide (26.5 g, 11.94 mmol) was added to a mixture of water and concentrated sulfuric acid, 150 ml (1:2). After 15 minutes the mixture was poured into water. The product was filtered off, washed with water and dried.
Workup
- filtrationThe product was filtered off
- washwashed with water
- customdried
Sources & evidence
- ORD record
- ord-4cd9d2f8740145f98a89fec295a82ac8
- Source dataset
- uspto-grants-1999_07
- Patent number
- US05922724
Reaction notes
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