HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3-Nitrophenyl)pyridine → 3-(Pyridin-3-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3-Nitrophenyl)pyridine | HCID 12181327 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(Pyridin-3-yl)aniline | HCID 459521 | — |
Reaction Steps
3-(3-pyridyl)-nitrobenzene (9.1 g, 45.5 mmol) in ethanol (125 ml) is hydrogenated at ambient pressure for 1.75 hours using Raney Nickel as the catalyst. Filtration of the resulting solution through celite followed by evaporation of solvent quantitatively yields 3-(3-pyridyl)aniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922724 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-e2c51de4f901493c8a5c8e21efe583c1 |
| Source note | uspto-grants-1999_07 |