Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) → 3-Bromo-2-methoxy-5-nitropyridine

HRID 583173

Reaction equation

HRID 583173 reaction equation
[OH:1][C:2]1[C:7]([Br:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=1.F[B-](F)(F)F.[CH3:17][O+](C)C>C(Cl)Cl>[CH3:17][O:1][C:2]1[C:7]([Br:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)HCID 178526832HCID 178526832, compound

Product 1

HCID 215844513-Bromo-2-methoxy-5-nitropyridine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was synthesized from 2-hydroxy-3-bromo-5-nitropyridine by the method of H. J. W. van den Haak et al, Recl.Trav. Chim. Pays-Bas 99(3), p83-87 (1980) using trimethyloxonium tetrafluoroborate in methylene chloride.

Sources & evidence

ORD record
ord-9cb449e7728f42ea8e324a1151c950ec
Source dataset
uspto-grants-1999_07
Patent number
US05929094

Linked notes

Loading…