HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dimethylbenzoic acid → 1-(3,4-Dimethylbenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dimethylbenzoic acid | HCID 12073 | — |
| Reactant | 1,2,3,4-Tetrahydro-2-methyl-4-quinolinol | HCID 147634 | — |
| Product | 1-(3,4-Dimethylbenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol | HCID 22339291 | 62.5% |
Reaction Steps
Starting with 2-methyl-1,2,3,4-tetrahydro-4-quinolinol (1.00 g, 6.12 mmol) synthesized in the published manner and 3,4-dimethylbenzoic acid (1.20 g, 7.96 mmol), the same procedure as shown in Reference Example 19 was repeated to give the titled compound (1.13 g, yield: 48%) as an oil. (cis:trans=1:1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06930104B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-b438aaa24d5e473fab42bdf6165d050d |
| Source note | uspto-grants-2005_08 |