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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587156Generated: October 27, 2026

Prolinamide, D- → (R)-1-[4-((3-(Sulfamoylmethyl)phenyl)amino)-1,3,5-triazin-2-yl]pyrrolidine-2-carboxamide

https://huagongshe.com/reaction/587156

Reaction equation

Participants

RoleNameHCIDCharge
ReactantProlinamide, D-HCID 447554—
Reactantrac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamideHCID 60197106—
Reactant3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamideHCID 86679822—
Product(R)-1-[4-((3-(Sulfamoylmethyl)phenyl)amino)-1,3,5-triazin-2-yl]pyrrolidine-2-carboxamideHCID 60197404—

Reaction Steps

B23 was obtained as a white powder by following the procedure reported for B4 using A1 and (R)-proline amide; yield: 65 mg (19%). MS (ES) C15H19N7O3S requires: 377. found: 378 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09226929B2
Source datasetuspto-grants-2016_01
ORD IDord-bd7988fcbf69419f80ce5bca8e415488
Source noteuspto-grants-2016_01