2-Morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-6-amine → N*2*,N*2*-Dimethyl-[1,2,4]triazolo[1,5-a]pyridine-2,6-diamine

HRID 588442

Reaction equation

HRID 588442 reaction equation
C(OC(=O)[NH:7][C:8]1[CH:9]=[CH:10][C:11]2[N:12]([N:14]=[C:15]([N:17]([CH3:19])[CH3:18])[N:16]=2)[CH:13]=1)(C)(C)C.N1(C2N=C3C=CC(N)=CN3N=2)CCOCC1>>[CH3:18][N:17]([CH3:19])[C:15]1[N:16]=[C:11]2[CH:10]=[CH:9][C:8]([NH2:7])=[CH:13][N:12]2[N:14]=1

Participants

3

Reactant 2

HCID 894644042-Morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-6-amineHCID 89464594(2-Dimethylamino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-carbamic acid tert-butyl ester

Product 1

HCID 89463594N*2*,N*2*-Dimethyl-[1,2,4]triazolo[1,5-a]pyridine-2,6-diamine

Procedure

Using (2-dimethylamino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-carbamic acid tert-butyl ester, this compound was prepared following the same method as for the synthesis of 2-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-6-ylamine. White solid (64 mg, 83%). MS: m/z=178 (M+H+).

Workup

  1. customthis compound was prepared

Sources & evidence

ORD record
ord-4d39d632910b4c6eb0829f583ea01402
Source dataset
uspto-grants-2016_01
Patent number
US09227970B2

Linked notes

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