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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 588641Generated: October 26, 2026

8-Azabicyclo(3.2.1)octane → (8-Azabicyclo[3.2.1]octan-3-yl]-4-chloro-3-methyl-5-phenyl-pyrazolo[3,4-c]pyridazine

https://huagongshe.com/reaction/588641

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Azabicyclo(3.2.1)octaneHCID 136097—
ReactantCID 86717276HCID 86717276—
Product(8-Azabicyclo[3.2.1]octan-3-yl]-4-chloro-3-methyl-5-phenyl-pyrazolo[3,4-c]pyridazineHCID 123430528—

Reaction Steps

Compound XIIIa was synthesized from 4-chloro-3-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine and nortropane following the general procedure for the Mitsunobu reaction described in Example 20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227976B2
Source datasetuspto-grants-2016_01
ORD IDord-75ab8f3f400b497284c243efda5dfbef
Source noteuspto-grants-2016_01