(3R)-3-Aminobutanoic acid → methyl (3R)-3-aminobutanoate hydrochloride

HRID 590572Notes

Reaction equation

HRID 590572 reaction equation
[ClH:1].[NH2:2][CH2:3][CH:4](C)[C:5]([O:7][CH3:8])=[O:6].N[C@H:11](C)CC(O)=O>>[ClH:1].[NH2:2][C@H:3]([CH3:11])[CH2:4][C:5]([O:7][CH3:8])=[O:6]

Participants

3

Reactant 2

HCID 5706670(3R)-3-Aminobutanoic acidHCID 13063725Methyl 3-amino-2-methylpropanoate hydrochloride

Product 1

HCID 53487347methyl (3R)-3-aminobutanoate hydrochloride

Procedure

Compound 57-B was prepared in analogy to compound W in Example 20 by using (R)-3-aminobutanoic acid instead of DL-3-aminoisobutyric acid.

Sources & evidence

ORD record
ord-5573627a214547f28fd0cf3b2da11ab2
Source dataset
uspto-grants-2016_01
Patent number
US09233978B2

Reaction notes

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