HCID 89768100, compound → HCID 89767941, compound
Reaction equation
C([O:8][C:9]1[CH:21]=[CH:20][C:12]2[C:13]([C:16]([O:18][CH3:19])=[O:17])=[CH:14][O:15][C:11]=2[CH:10]=1)C1C=CC=CC=1>[Pd].CO>[OH:8][C:9]1[CH:21]=[CH:20][C:12]2[CH:13]([C:16]([O:18][CH3:19])=[O:17])[CH2:14][O:15][C:11]=2[CH:10]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
To a mixture of methyl 6-(benzyloxy)-1-benzofuran-3-carboxylate (10 g) and MeOH (200 mL) was added 10% Pd—C (2 g). The mixture was stirred under hydrogen atmosphere overnight. The catalyst was removed by filtration. The filtrate was concentrated in vacuo to give the title compound (7.08 g).
Workup
- customThe catalyst was removed by filtration
- concentrationThe filtrate was concentrated in vacuo
Sources & evidence
- ORD record
- ord-68e75194a4544eb6812f21222fb6f7f2
- Source dataset
- uspto-grants-2016_01
- Patent number
- US09238639B2
Reaction notes
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