2,6-Dimethylpyridine N-oxide → 1-Methoxy-2,6-dimethyl-pyridinium tetrafluoroborate

HRID 591801

Reaction equation

HRID 591801 reaction equation
[N+:1]1([O-:9])[C:2]([CH3:8])=[CH:3][CH:4]=[CH:5][C:6]=1[CH3:7].[F:10][B-:11]([F:14])([F:13])[F:12].[CH3:15][O+](C)C>ClCCl>[F:10][B-:11]([F:14])([F:13])[F:12].[CH3:15][O:9][N+:1]1[C:6]([CH3:7])=[CH:5][CH:4]=[CH:3][C:2]=1[CH3:8]

Participants

4

Reactant 2

HCID 140832,6-Dimethylpyridine N-oxideHCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)

Product 1

HCID 153536581-Methoxy-2,6-dimethyl-pyridinium tetrafluoroborate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 2,6-lutidine N-oxide (24.0 g, 0.20 mol) in anhydrous dichloromethane (400 mL) was added to trimethyloxonium tetrafluoroborate (29.6 g, 0.20 mol) at room temperature under nitrogen atmosphere and the reaction mixture was stirred at room temperature for 3 hours. The mixture was concentrated in vacuo to give the crude product, 1-methoxy-2,6-dimethyl-pyridinium tetrafluoroborate.

Workup

  1. concentrationThe mixture was concentrated in vacuo

Sources & evidence

ORD record
ord-6d6b66f2351f4bffaa0937230a7364bf
Source dataset
uspto-grants-2016_01
Patent number
US09238640B2

Linked notes

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