HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dibenzo(b,d)thiophene-2-carbaldehyde → 1-(Dibenzo[b,d]thiophen-2-ylmethyl)-5-(2,6-dimethoxyphenyl)-3-methylpyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dibenzo(b,d)thiophene-2-carbaldehyde | HCID 641360 | — |
| Reactant | Ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate | HCID 69085588 | — |
| Product | 1-(Dibenzo[b,d]thiophen-2-ylmethyl)-5-(2,6-dimethoxyphenyl)-3-methylpyrrolidin-2-one | HCID 86695667 | — |
Reaction Steps
Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate with synthesized dibenzo[b,d]thiophene-2-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.99 min.; [M+H]+: 431.87 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-13b10fd70df04204a33dafa5c96e0e63 |
| Source note | uspto-grants-2016_01 |