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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 596205Generated: October 24, 2026

Dimethylformamide → 1-Methyl-2-(5-aminomethylhexylisoxazol-3-yl)-5-nitroimidazole

https://huagongshe.com/en/reaction/596205

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant1-ChlorohexaneHCID 10992—
Reactant1-Methyl-2-(5-aminoethylhexylisoxazol-3-yl)-5-nitroimidazoleHCID 68120562—
Product1-Methyl-2-(5-aminomethylhexylisoxazol-3-yl)-5-nitroimidazoleHCID 20362476—

Reaction Steps

The product prepared above is treated in a similar fashion with hexyl chloride in dimethylformamide for 2 hours. The recrystallized product is identified as 1-methyl-2-(5-aminoethylhexylisoxazol-3-yl)-5-nitroimidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04010176
Source datasetuspto-grants-1977_03
ORD IDord-689eb3082301414b975a2d0afb36a4f0
Source noteuspto-grants-1977_03