HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 2-(4-Fluorophenyl)benzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | 4-Fluoro-N-(2-hydroxyphenyl)benzamide | HCID 579383 | — |
| Product | 2-(4-Fluorophenyl)benzoxazole | HCID 2953623 | — |
Reaction Steps
4-Fluoro-N-(2-hydroxyphenyl) benzamide (IVa), acid (H2SO4, methanesulfonic acid (MeSO3H) or p-toluene sulfonic acid (p-TsOH)) and solvent were heated under the conditions outlined in table 2 with a Dean-Stark tube.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440935B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-cb228d2e3ac846379ad65085c5e02226 |
| Source note | uspto-grants-2016_09 |