Methyl isothiocyanate → N-Methyl-N'-[2-(2,6-dimethylpiperidino)-ethyl]-thiourea

HRID 596592

Reaction equation

[NH2:1][CH2:2][CH2:3][N:4]1[CH:9]([CH3:10])[CH2:8][CH2:7][CH2:6][CH:5]1[CH3:11].[CH3:12][N:13]=[C:14]=[S:15]>>[CH3:12][NH:13][C:14]([NH:1][CH2:2][CH2:3][N:4]1[CH:9]([CH3:10])[CH2:8][CH2:7][CH2:6][CH:5]1[CH3:11])=[S:15]

Participants

Reactant 2

HCID 11167Methyl isothiocyanate

HCID 31492662,6-Dimethyl-1-piperidineethanamine

Product 1

HCID 21450386N-Methyl-N'-[2-(2,6-dimethylpiperidino)-ethyl]-thiourea

Procedure

By the general method described in Example 1, 1-(2-aminoethyl)-2,6-dimethylpiperidine is reacted with methyl isothiocyanate to give the title compound.

Sources & evidence

ORD record: ord-c1fa40e555c540e3ab86d433f0d3e62d
Source dataset: uspto-grants-1977_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04011331

Linked notes

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