Phenetole → 2-Methoxy-5-methylphenol

HRID 597349

Reaction equation

HRID 597349 reaction equation
C([O:3]C1C=CC=CC=1)C.[CH3:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=1>>[CH3:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][C:13]=1[OH:3]

Participants

3

Reactant 2

HCID 7674PhenetoleHCID 77314-Methylanisole

Product 1

HCID 145192-Methoxy-5-methylphenolYield 46.9%

Procedure

The reaction was carried out in the same manner as in Example 6 except that ethoxybenzene was replaced by 150 g. (1229.5 m.moles) of p-methoxytoluene and 4.11 g. (29.8 m.moles) of 2-methoxy-5-methylphenol was obtained in a yield of 46.9 %.

Sources & evidence

ORD record
ord-16ee44319c6f4016bc01328e5f35cb28
Source dataset
uspto-grants-1977_03
Patent number
US04013727

Linked notes

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