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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 59795Generated: October 26, 2026

Methyl 4-Formylbenzoate → tert-Butyl 4-((4-chlorophenethyl)(4-(methoxycarbonyl)benzyl)amino)piperidine-1-carboxylate

https://huagongshe.com/reaction/59795

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-FormylbenzoateHCID 15294—
Reactant2-(4-Chlorophenyl)ethylamineHCID 67430—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Producttert-Butyl 4-((4-chlorophenethyl)(4-(methoxycarbonyl)benzyl)amino)piperidine-1-carboxylateHCID 121422786—

Reaction Steps

The title compound was prepared according to Procedure 1B starting from N-Boc-piperid-4-one, 2-(4-chlorophenyl)ethylamine, and methyl 4-formylbenzoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440953B2
Source datasetuspto-grants-2016_09
ORD IDord-160d257143854337814bdb442468d826
Source noteuspto-grants-2016_09