Methyl 3-cyano-4-methylbenzoate → Methyl 3-(aminomethyl)-4-methylbenzoate hydrochloride

HRID 59892

Reaction equation

HRID 59892 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[CH3:13])[C:6]([O:8][CH3:9])=[O:7])#[N:2].[ClH:14].NCC1C=C(C=C(OC)C=1)C(OC)=O>>[ClH:14].[NH2:2][CH2:1][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[CH3:13])[C:6]([O:8][CH3:9])=[O:7]

Participants

3

Reactant 2

HCID 11819538Methyl 3-cyano-4-methylbenzoateHCID 118366264Methyl 3-(aminomethyl)-5-methoxybenzoate hydrochloride

Product 1

HCID 118366194Methyl 3-(aminomethyl)-4-methylbenzoate hydrochloride

Procedure

Methyl 3-(aminomethyl)-4-methylbenzoate hydrochloride was prepared from methyl 3-cyano-4-methylbenzoate in an analogous manner to Intermediate 2.

Sources & evidence

ORD record
ord-f00bafaff9cc47818e17d569d7ab4eee
Source dataset
uspto-grants-2016_09
Patent number
US09440949B2

Linked notes

Loading…