Methyl 3-cyano-5-methylbenzoate → Methyl 3-(aminomethyl)-5-methylbenzoate hydrochloride

HRID 59895

Reaction equation

HRID 59895 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([CH3:13])[CH:12]=1)[C:6]([O:8][CH3:9])=[O:7])#[N:2].[ClH:14].NCC1C=C(C=C(OC)C=1)C(OC)=O>>[ClH:14].[NH2:2][CH2:1][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([CH3:13])[CH:12]=1)[C:6]([O:8][CH3:9])=[O:7]

Participants

3

Reactant 2

HCID 53399305Methyl 3-cyano-5-methylbenzoateHCID 118366264Methyl 3-(aminomethyl)-5-methoxybenzoate hydrochloride

Product 1

HCID 118366266Methyl 3-(aminomethyl)-5-methylbenzoate hydrochloride

Procedure

Methyl 3-(aminomethyl)-5-methylbenzoate hydrochloride was prepared from methyl 3-cyano-5-methylbenzoate in an analogous manner to Intermediate 2.

Sources & evidence

ORD record
ord-dc18719ab1344ca4953750613a60c359
Source dataset
uspto-grants-2016_09
Patent number
US09440949B2

Linked notes

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