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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601166Generated: October 25, 2026

2-Amino-5-bromobenzenesulfonamide → N-[2-(aminosulfonyl)phenyl]-4-hydroxy-2-oxo-1-propoxy-1,2-dihydroquinoline-3-carboxamide

https://huagongshe.com/reaction/601166

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-bromobenzenesulfonamideHCID 820700—
ReactantEthyl 1-benzyl-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylateHCID 54729304—
ReactantEthyl 4-hydroxy-2-oxo-1-propoxy-1,2-dihydroquinoline-3-carboxylateHCID 67063576—
ProductN-[2-(aminosulfonyl)phenyl]-4-hydroxy-2-oxo-1-propoxy-1,2-dihydroquinoline-3-carboxamideHCID 67063695—

Reaction Steps

The title compound is prepared according to the procedure of Example 84C substituting the product of Example 172D for the product of Example 84B and substituting 2-aminosulfonamide for the product of Example 84A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902203B2
Source datasetuspto-grants-2011_03
ORD IDord-24a914d39abf45a7a65cd0da851c6378
Source noteuspto-grants-2011_03