HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodo-1-methyl-1H-pyrazole-5-carboxylic acid → 4-(6-cyanopyridin-2-yl)-1-methyl-1H-pyrazole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodo-1-methyl-1H-pyrazole-5-carboxylic acid | HCID 673687 | — |
| Reactant | 6-Bromopyridine-2-carbonitrile | HCID 15100859 | — |
| Product | 4-(6-cyanopyridin-2-yl)-1-methyl-1H-pyrazole-5-carboxylic acid | HCID 90383454 | 0.5% |
Reaction Steps
Using 6-bromopicolinonitrile (0.73 g) and 4-iodo-1-methyl-1H-pyrazole-5-carboxylic acid (1 g), the title compound (4.7 mg) was obtained in the form of a colorless solid by the same method as that of (Example 3.22) <Step 1> or a method equivalent thereto.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440970B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-4f71b1a0ad924789a5c437367e9bd3cf |
| Source note | uspto-grants-2016_09 |