HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → Benzenesulfonyl-acetic acid hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Methyl phenylsulfonyl acetate | HCID 555619 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Benzenesulfonyl-acetic acid hydrazide | HCID 11378890 | 99.4% |
Reaction Steps
To a stirred solution of 5.0 g (0.023 mol) of benzenesulfonyl-acetic acid methyl ester in 10 mL of MeOH at RT, 3.50 g (0.070 mol, 3 eq) of hydrazine hydrate were added. After one hour, the solvent and the excess of hydrazine were removed under reduced pressure, yielding 4.90 g (quantitative) of benzenesulfonyl-acetic acid hydrazide as a colorless oil, MS: 232 (MNH4+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07906546B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-1db2cf388b6442e6be5c771eb371d57b |
| Source note | uspto-grants-2011_03 |