HCID 86615567, compound → ethyl (2R)-2-amino-2-phenylpropanoate

Reaction equation

C([NH:3][C@@:4]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)([CH3:8])[C:5]([OH:7])=[O:6])=O.C(N[C@:18](C1C=CC=CC=1)(C)[C:19](O)=O)=O>>[NH2:3][C@@:4]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)([CH3:8])[C:5]([O:7][CH2:18][CH3:19])=[O:6]

Participants

Reactant 2

HCID 86615567HCID 86615567, compound

HCID 86615570HCID 86615570, compound

Product 1

HCID 57186408ethyl (2R)-2-amino-2-phenylpropanoate

Procedure

The title compound was prepared (1.12 g, 76%) by the procedure of Example 445C substituting the product of Example 450A for the product of Example 445B.

Sources & evidence

ORD record: ord-356a2617aaa34a8aa15ce4c75e810681
Source dataset: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07910595B2

Reaction notes

Loading…