4-Chloro-3-nitrotoluene → 4-Ethyl-2-nitro-1-phenylsulfanyl-benzene

HRID 607275

Reaction equation

[C:1]1([S-:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Na+].Cl[C:10]1[CH:15]=[CH:14][C:13]([CH2:16][CH3:17])=[CH:12][C:11]=1[N+:18]([O-:20])=[O:19].ClC1C=CC(C)=CC=1[N+]([O-])=O>>[CH2:16]([C:13]1[CH:14]=[CH:15][C:10]([S:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[C:11]([N+:18]([O-:20])=[O:19])[CH:12]=1)[CH3:17]

Participants

Reactant 3

HCID 69764-Chloro-3-nitrotoluene

HCID 4110039Sodium benzenethiolate

HCID 137921561-Chloro-4-ethyl-2-nitro-benzene

Product 1

HCID 574699134-Ethyl-2-nitro-1-phenylsulfanyl-benzene

Procedure

Sodium thiophenolate was reacted with 1-Chloro-4-ethyl-2-nitro-benzene according to the procedure from Example 5H substituting 1-Chloro-4-ethyl-2-nitro-benzene for 4-chloro-3-nitrotoluene to provide 4-Ethyl-2-nitro-1-phenylsulfanyl-benzene which was reduced according to the procedure from Example 5I to provide the title compound.

Sources & evidence

ORD record: ord-54d11cb98c094a3eb4ceb54b11cb6cc4
Source dataset: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07915411B2

Linked notes

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