HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → (S)-N-{[3-(diethylamino)propyl](oxido)phenyl--sulfanylidene}-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 76585264 | — |
| Product | (S)-N-{[3-(diethylamino)propyl](oxido)phenyl--sulfanylidene}-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 57657902 | — |
Reaction Steps
In a manner similar to that described for Example 508, N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide and diethylamine were converted to the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915443B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-75283d8952c54c4ab8ac3701f0268a6e |
| Source note | uspto-grants-2011_03 |