HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-methyl-5-phenyl-1,3-thiazole-4-carboxylic Acid → rac-cis-(2-(Aminomethyl)-3-methylpiperidin-1-yl)(2-methyl-5-phenylthiazol-4-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-methyl-5-phenyl-1,3-thiazole-4-carboxylic Acid | HCID 943535 | — |
| Reactant | cis-N-Boc-1-(3-methylpiperidin-2-YL)methanamine | HCID 95378400 | — |
| Product | rac-cis-(2-(Aminomethyl)-3-methylpiperidin-1-yl)(2-methyl-5-phenylthiazol-4-yl)methanone | HCID 131737123 | — |
Reaction Steps
The title compound was synthesized following the same general protocol as described in Example 11 using rac-cis-tert-butyl ((3-methylpiperidin-2-yl)methyl)carbamate and 2-methyl-5-phenylthiazole-4-carboxylic acid. MS (ESI) 330.08 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440982B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-2bba2d6b6aaa4105b761dc08b5fc89f7 |
| Source note | uspto-grants-2016_09 |