o-Phenylbenzoic acid → Ethyl 2-(2-(biphenylcarbonyl)octahydro-1H-isoindol-1-yl)acetate

HRID 60837

Reaction equation

HRID 60837 reaction equation
[CH:1]1([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:9]2[CH:4]([CH2:5][CH2:6][CH2:7][CH2:8]2)[CH2:3][NH:2]1.[C:16]1([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:17]([C:22](O)=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=1>>[C:16]1([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:17]([C:22]([N:2]2[CH2:3][CH:4]3[CH:9]([CH2:8][CH2:7][CH2:6][CH2:5]3)[CH:1]2[CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 70357o-Phenylbenzoic acidHCID 89740797Octahydro-1H-isoindole-1-acetic acid ethyl ester

Product 1

HCID 89740940Ethyl 2-(2-(biphenylcarbonyl)octahydro-1H-isoindol-1-yl)acetate

Procedure

Ethyl 2-(2-(biphenylcarbonyl)octahydro-1H-isoindol-1-yl)acetate was prepared according to general procedure A using ethyl 2-(octahydro-1H-isoindol-1-yl)acetate and biphenyl-2-carboxylic acid.

Sources & evidence

ORD record
ord-c1cde3ceea3b4906999d2b6b4feef8f2
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Linked notes

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