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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60920Generated: October 26, 2026

Iodopyrazine → Methyl 5-methyl-2-(pyrazin-2-yl)benzoate

https://huagongshe.com/reaction/60920

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodopyrazineHCID 642841—
ReactantMethyl 5-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoateHCID 46856403—
ReactantMethyl 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoateHCID 117727848—
ProductMethyl 5-methyl-2-(pyrazin-2-yl)benzoateHCID 117728053—

Reaction Steps

The title compound was synthesized following the same general protocol as described for methyl 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoate in Example A1, using methyl 5-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate and using 2-iodopyrazine. ESI-MS (m/z): 229 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-49df807a707541b29b8c7e7fd0c9622e
Source noteuspto-grants-2016_09