5-Bromo-1-methyl-1H-imidazole → 5-Methyl-2-(1-methyl-1H-imidazol-5-yl)benzoic acid

HRID 60933

Reaction equation

HRID 60933 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:11]2[CH:16]=[N:15][CH:14]=[CH:13][N:12]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].BrC1N(C)C=NC=1>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:11]2[N:12]([CH3:13])[CH:14]=[N:15][CH:16]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 15152585-Bromo-1-methyl-1H-imidazoleHCID 811116085-Methyl-2-(2-pyrazinyl)benzoic acid

Product 1

HCID 1177279835-Methyl-2-(1-methyl-1H-imidazol-5-yl)benzoic acid

Procedure

The title compound was prepared following the same general protocol as described for 5-methyl-2-(pyrazin-2-yl)benzoic acid in Example A19, starting from 5-bromo-1-methyl-1H-imidazole. ESI-MS (m/z): 217 [M+1]+.

Sources & evidence

ORD record
ord-6664ef79221c4f92988b3efbb48dd240
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Linked notes

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