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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60951Generated: October 26, 2026

2-Chloro-4-methylpyrimidine → 5-Methyl-2-(4-methyl-2-pyrimidinyl)benzoic acid

https://huagongshe.com/reaction/60951

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-methylpyrimidineHCID 11629607—
Reactant5-Methyl-2-(2-pyrazinyl)benzoic acidHCID 81111608—
Product5-Methyl-2-(4-methyl-2-pyrimidinyl)benzoic acidHCID 117727641—

Reaction Steps

The title compound was prepared following the same general protocol as described for 5-methyl-2-(pyrazin-2-yl)benzoic acid in Example A19, starting from 2-chloro-4-methylpyrimidine. ESI-MS (m/z): 229 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-61d3d908da0545979f2fd95da5c839b6
Source noteuspto-grants-2016_09