HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indole-3-carboxylic acid, 2-chloro- → N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indole-3-carboxylic acid, 2-chloro- | HCID 99521 | — |
| Reactant | N-[(1-n butyl-4-piperidyl)methyl] indole-3-carboxamide | HCID 10591304 | — |
| Product | N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide | HCID 22096969 | — |
Reaction Steps
2-Chloroindole-3-carboxylic acid (L. Marchetti and A Andreani, Ann. Chim. (Rome), 1973, 63, 681) was converted to its acid chloride and reacted with N-(1-n butyl-4-piperidyl)methylamine (D1) using the procedure of Description 1b to afford N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998409 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-a21d3270672b4aa1a7ed054c7bdf51f9 |
| Source note | uspto-grants-1999_12 |