2-Bromo-5-methylpyridine → 5-Methyl-2-(5-methylpyridin-2-yl)benzoic acid

HRID 61042

Reaction equation

HRID 61042 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5](C2C=NC=CN=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].Br[C:18]1[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][N:19]=1>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:18]2[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][N:19]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 5642162-Bromo-5-methylpyridineHCID 811116085-Methyl-2-(2-pyrazinyl)benzoic acid

Product 1

HCID 1177277405-Methyl-2-(5-methylpyridin-2-yl)benzoic acid

Procedure

The title compound was synthesized following the same general protocol as described for 5-methyl-2-(pyrazin-2-yl)benzoic acid in Example A19, using 2-bromo-5-methylpyridine. ESI-MS (m/z): 228 [M+1]+.

Sources & evidence

ORD record
ord-2c3e2a4a70ce44ff85eaf6a7d8e61505
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Linked notes

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