9-(2-Thienyl)-8-nonenoic acid → 9-(2-Thienyl)-nonanoic acid
Reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=[CH:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15]>[Pd]>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
This compound was synthesized from 9-(2-thienyl)-8-nonenoic acid (1.19 g, 5 mmol) by a hydrogenation reaction using Pd/C (120 mg). Crystallization afforded the product (1.05 g, 88%) as white crystals (mp 32-33° C.); IR: 3400-2500, 1715, 705 cm-1 ; 1H-NMR: 1.35 (m, 12 H), 2.35 (t, 2 H), 2.85 (t, 2 H), 6.95 (m, 3 H), 10.35 (bs, 1 H). Anal. Calcd. for C13H20SO2 : C, 64.96, H, 8.39%; Found: C, 64.81, H, 8.43%.
Workup
- customCrystallization
Sources & evidence
- ORD record
- ord-be91a62847614125b043416a826d0c80
- Source dataset
- uspto-grants-1999_12
- Patent number
- US06001869
Reaction notes
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