Thionyl Chloride → 2-Methoxy-6-methylbenzoyl chloride

HRID 611704

Reaction equation

HRID 611704 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:4]=1[C:5](O)=[O:6].S(Cl)([Cl:15])=O>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:4]=1[C:5]([Cl:15])=[O:6]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 2731702-Methoxy-6-methylbenzoic acid

Product 1

HCID 128926752-Methoxy-6-methylbenzoyl chloride

Procedure

A mixture of 1A (1.7 g, 10.2 mmol) and thionyl chloride (2 ml) is heated under reflux for 1 hour. The mixture is concentrated and the resulting benzoylchloride is used without further purification.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 1 hour
  3. concentrationThe mixture is concentrated
  4. customthe resulting benzoylchloride is used without further purification

Sources & evidence

ORD record
ord-450ca4c394d9487ebfe0cf542fbc9cb8
Source dataset
uspto-grants-1999_12
Patent number
US06001883

Linked notes

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