3-Bromo-1,1,1-trifluoropropane → HCID 178447766, compound

HRID 612325

Reaction equation

HRID 612325 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([O:8][Si](C(C)(C)C)(C)C)=[CH:4][CH:3]=1.C([Si:19]1([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34]C=2)[CH2:24][CH2:23][CH:22]([CH:25]2[CH2:30][CH2:29][C:28](=O)[CH2:27][CH2:26]2)[CH2:21][CH2:20]1)CC.Br[CH2:39][CH2:40][C:41]([F:44])([F:43])[F:42]>>[CH2:32]([Si@H:19]1[CH2:20][CH2:21][C@H:22]([C@H:25]2[CH2:26][CH2:27][C@H:28]([C:2]3[CH:3]=[CH:4][C:5]([O:8][CH2:39][CH2:40][C:41]([F:44])([F:43])[F:42])=[CH:6][CH:7]=3)[CH2:29][CH2:30]2)[CH2:23][CH2:24]1)[CH2:37][CH2:36][CH2:35][CH3:34]

Participants

4

Reactant 3

HCID 27251143-Bromo-1,1,1-trifluoropropaneHCID 4227167(4-Bromophenoxy)(tert-butyl)dimethylsilaneHCID 110343904-(4-Phenyl-4-n-propyl-4-silacyclohexyl)cyclohexanone

Product 1

HCID 178447766HCID 178447766, compound

Procedure

The general procedure of Example 1 was repeated using 1-bromo-4-(t-butyldimethylsiloxy)benzene, 4-(4-n-propyl-4-phenyl-4-silacyclohexyl)cyclohexanone and 1-bromo-3,3,3-trifluoro-n-propane, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-091f4ff2ae7a448c8ef21fbe2425ebc5
Source dataset
uspto-grants-1999_12
Patent number
US06004478

Linked notes

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