3-Bromo-1,1,2,2-tetrafluoropropane → HCID 178447750, compound
Reaction equation
C([Si:6]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16]C=2)[CH2:11][CH2:10][CH:9]([CH:12]=O)[CH2:8][CH2:7]1)=CCCC.[Br-].[O:21]([C:29]1[CH:54]=[CH:53][C:32]([CH2:33][P+](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=[CH:31][CH:30]=1)[Si](C(C)(C)C)(C)C.Br[CH2:56][C:57]([F:62])([F:61])[CH:58]([F:60])[F:59]>>[F:61][C:57]([F:62])([CH:58]([F:60])[F:59])[CH2:56][O:21][C:29]1[CH:30]=[CH:31][C:32]([CH2:33][CH2:12][C@H:9]2[CH2:8][CH2:7][Si@H:6]([CH2:14][CH2:19][CH2:18][CH:17]=[CH2:16])[CH2:11][CH2:10]2)=[CH:53][CH:54]=1Participants
4
Procedure
The general procedure of Example 56 was repeated using 4-n-pentenyl-4-phenyl-4-silacyclohexane carbaldehyde, 4-(t-butyldimethylsiloxy)benzyltriphenylphosphonium bromide, and 1-bromo-2,2,3,3-tetrafluoropropane, thereby obtaining the intended compound.