Methyl iodide → HCID 19593118, compound
Reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]([OH:24])([CH2:18][N:19]1[CH:23]=[N:22][CH:21]=[N:20]1)[C:10]([F:17])([F:16])[S:11][CH2:12][CH2:13][O:14]C.F[C:26]1[CH:31]=[C:30](F)[CH:29]=[CH:28][C:27]=1[C:33](O)(CN1C=NC=N1)C(F)(F)SCCO.CI.C(Cl)C1C=CC=CC=1>>[CH2:33]([O:24][C:9]([C:3]1[CH:4]=[CH:5][C:6]([F:8])=[CH:7][C:2]=1[F:1])([CH2:18][N:19]1[CH:23]=[N:22][CH:21]=[N:20]1)[C:10]([S:11][CH2:12][CH2:13][OH:14])([F:17])[F:16])[C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:26]=1Participants
5
Procedure
In a similar manner to Example 1 except that 2-(2,4-difluorophenyl)-1,1-difluoro-1[(2-methoxyethyl)thio]-3-(1H-1,2,4-triazol-1-yl)-2-propanol was replaced with 2-(2,4-difluorophenyl)-1,1-difluoro-1-[(2-hydroxyethyl)thio]-3-(1H-1,2,4-triazol-1-yl)-2-propanol and methyl iodide was replaced with benzyl chloride, the experiment was carried out, whereby 2-{[2-(benzyloxy)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)propyl]thio}-1-ethanol was obtained as a colorless oil.