HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenyl-1-propanol → 2-(2-Phenylpropoxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenyl-1-propanol | HCID 14295 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Catalyst | Tetrabutylammonium Bromide | HCID 74236 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-(2-Phenylpropoxy)acetic acid | HCID 18779048 | 77.1% |
Reaction Steps
The subtitle compound (14.95 g) was prepared according to the procedure in example 6 part a using 2-phenyl-1-propanol (13.6 g), t-butylbromoacetate (19.5 g), tetrabutylammoniumbromide (3.2 g), toluene (70 ml), 50% aqueous sodium hydroxide (25 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06008365 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-1dc0d09ba33d4def9ac4e2c4d6dd760b |
| Source note | uspto-grants-1999_12 |