D-phenylalanine hydrochloride → D-Phenylalanine

Participants

Reaction Steps

The D-phenylalanine hydrochloride having an optical purity of 99.2% which was obtained in Example 8 (74.8 mmol) was dissolved in 70 ml of pure water at 30° C., and the solution was neutralized to a pH of about 5.5 with a 20% NaOH aqueous solution for crystallization. The slurry containing the precipitated crystals was cooled to room temperature, followed by filtration by suction to give 61.4 mmol of D-phenylalanine having an optical purity of 99.9%.

Provenance & Evidence